KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells
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چکیده
منابع مشابه
KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells.
OBJECTIVE Atheroprotective blood flow induces expression of anti-inflammatory Krüppel-like factor 2 (KLF2) and activates antioxidant transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) in vascular endothelium. Previously, we obtained KLF2-induced gene expression profiles in ECs, containing several Nrf2 target genes. Our aim was to investigate the role of KLF2 in shear stress...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2008
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.108.165811